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Douglas G. McNeel: stay current reading research literature, there is no substitute for hard work! More >>
ERAS and Tubeless—Michael Haddock: the past and future of proton beam More >>
Professor Norman Wolmark: perseverance sometimes pays off More >>


Ensartinib (X-396) a novel drug for anaplastic lymphoma kinase-positive non-small cell lung cancer patients: we need smart trials to avoid wasting good bullets
Gianluca Spitaleri, Antonio Passaro, Filippo de Marinis
Digging into lorlatinib resistance in ALK-positive lung cancer: an editorial
Francesco Facchinetti, Marcello Tiseo
Does bisphosphonate treatment reduce the risk of future cancer?
Michael Pazianas, Bo Abrahamsen
Ensartinib (X-396): what does it add for patients with ALK-rearranged NSCLC
Tianhong Li, Weijie Ma, Eddie C. Tian
Perineural invasion in oral cancer: challenges, controversies and clinical impact
Sabrina Daniela da Silva, Luiz Paulo Kowalski
Recent changes in the American Joint Commission Cancer staging of human papilloma virus related oropharyngeal cancer: validating the present and envisioning the future
Brett A. Miles
The dawn of a universal language for an emerging malignancy
Junichi Shindoh
The 8th Edition of the American Joint Committee on Cancer (AJCC8) Staging Manual: any improvement in the prognostication of oral tongue cancer?
Alhadi Almangush, Tuula Salo
Considering sarcoma staging systems and their implications to personalized care
Rick L. Haas, Michiel A. J. van de Sande
Occult breast cancer: the uncommon presentation of a common disease
Angela Toss, Luca Moscetti, Stefano Cascinu
Breast cancer prognostic staging and internal mammary lymph node metastases: a brief overview
Jennifer K. Plichta
Staging systems and nomograms in soft tissue sarcoma: outcome prediction by categorization or personalization?
William W. Tseng, Sandro Pasquali, James S. Hu, Lawrence R. Menendez, Alessandro Gronchi
Unlocking the potential with the use of check-point inhibitor immunotherapies in metastatic prostate cancer
Swaroop Revannasiddaiah, Ishu Gupta, Santhosh Kumar Devadas
Emerging new predictive biomarkers in metastatic breast cancer: Caveolin-1 and weekly nab-paclitaxel plus gemcitabine, are we on for tomorrow?
Francesco Ricci, Christophe Le Tourneau
What can National Registry data tell us about occult breast cancer?
John Benjamin Wild, Steven Thrush, Raghavan Vidya
Impact of hypochloremia in resected colorectal cancer patients
Mai Tsutsui, Seiichiro Yamamoto
A step ahead on CTHRC1, and not just reinventing the wheel!
Siddharth Turkar, Anant Ramaswamy, Vikas Ostwal


Can EGFR mutation status evolve with chemotherapy?
Eric S. Kim, David J. Stewart, Alok A. Khorana

Original Article

Prostate carcinoma in transgenic Lewis rats - a tumor model for evaluation of immunological treatments
Laura E. Johnson, Jordan T. Becker, Jason A. Dubovsky, Brian M. Olson, Douglas G. McNeel

Review Article

The spectrum of clinical trials aiming at personalizing medicine
Christophe Le Tourneau, Maud Kamal, Marie Alt, Loic Verlingue, Vincent Servois, Marie-Paule Sablin, Nicolas Servant, Xavier Paoletti
Drug designs fulfilling the requirements of clinical trials aiming at personalizing medicine
Sumithra J. Mandrekar, Daniel J. Sargent
From genomic data analysis to drug development: a new generation of trials using molecular marker assessment in breast cancer
Sophie Doisneau-Sixou, Nadia Harbeck
Melanoma adjuvant therapy
Prashanth M. Thalanayar, Sanjiv S. Agarwala, Ahmad A. Tarhini
Genotyping of cutaneous melanoma
Isabella C. Glitza, Michael A. Davies
Treatment of KIT-mutated metastatic mucosal melanoma
Kevin B. Kim, Anas Alrwas
New approaches in primary central nervous system lymphoma
Eleanor Fraser, Katherine Gruenberg, James L. Rubenstein
Molecular and clinical implementations of ovarian cancer mouse avatar models
Amira A. Zayed, Sumithra J. Mandrekar, Paul Haluska
An overview of the design and conduct of the BATTLE trials
Suyu Liu, J. Jack Lee
Designing a definitive trial for adjuvant targeted therapy in genotype defined lung cancer: the ALCHEMIST trials
Ryan S. Alden, Sumithra J. Mandrekar, Geoffrey R. Oxnard
Risk- and response-adapted strategies for the management of Hodgkin lymphoma
Marcus Remer, Peter W. M. Johnson
Prognostic scores for brain metastasis patients: use in clinical practice and trial design
Vyshak Alva Venur, Manmeet S. Ahluwalia
Strategies for preservation of memory function in patients with brain metastases
Nicholas B. Dye, Vinai Gondi, Minesh P. Mehta
Management of neoplastic meningitis
Patrick Roth, Michael Weller
Design and statistical principles of the SHIVA trial
Xavier Paoletti, Bernard Asselain, Maud Kamal, Nicolas Servant, Philippe Huppé, Ivan Bieche, Christophe Le Tourneau
Autologous tracheal replacement for cancer
Dominique Fabre, Elie Fadel, Sacha Mussot, Frederic Kolb, Nicolas Leymarie, Olaf Mercier, Thierry Le Chevalier, Philippe G. Dartevelle
The staging value of sentinel lymph node biopsy for breast cancer: translating pathologic findings to clinical practice
Jean Bao, Cory Donovan, Alice Chung, Armando E. Giuliano
HER2-positive breast cancer, how far away from the cure?—on the current situation of anti-HER2 therapy in breast cancer treatment and survival of patients
Ning Liao
Training of breast surgical oncologists
Mediget Teshome, Henry M. Kuerer
The way to precision medicine of our team
Fengrui Xu, Xiaodi Wang, Zefei Jiang
Genetic testing for hereditary breast cancer in Asia—moving forward
Ava Kwong

Review Articles

Prevention of colorectal cancer and dietary management
Ningqi Hou, Dezheng Huo, James J. Dignam
Stage II colon cancer
David N. Church, Rachel Midgley, David J. Kerr
Mining the ACCENT database: a review and update
Lindsay A. Renfro, Qian Shi, Daniel J. Sargent
Status of hepatocellular carcinoma in South Korea
Seung Kew Yoon, Hoo Geun Chun

Statistics in Oncology Clinical Trials

Adaptive randomized phase II design for biomarker threshold selection and independent evaluation
Lindsay A. Renfro, Christina M. Coughlin, Axel M. Grothey, Daniel J. Sargent
Adaptive clinical trial designs in oncology
Yong Zang, J. Jack Lee
Statistical aspect of translational and correlative studies in clinical trials
Herbert Pang, Xiaofei Wang

Updates on Surgical Oncology

Clinical trials in lung cancer surgery and research cooperation
Wen-Zhao Zhong, Hao-Ran Zhai, Yi-Long Wu

Below are the latest Chinese Clinical Oncology articles published online ahead of print publication.


Original Article