About cco

Manuscript Submission


Contact us

Focused Issues more

Vol 5, No 2 (April 2016): Nasopharyngeal Carcinoma-Guest Editors: Joseph Wee, Yoke-Lim Soong,... More >>
Vol 4, No 4 (December 2015): Lung Cancer - Guest Editors: Jean-Pierre Armand and Liya Ju More >>
Vol 4, No 3 (September 2015): biomarker-based clinical trial designs in oncology - Guest Editors:... More >>

Charles M. Balch: Surgical Oncology Column more

Clinical trials in lung cancer surgery and research cooperation: With China having an... More >>
Training and certification of the surgical oncologist: Surgical Oncology has evolved as a... More >>


Nasopharyngeal carcinoma—past lessons and a glimpse into the future
Joseph Tien Seng Wee, Yoke Lim Soong, Melvin Lee Kiang Chua

Review Article

Genetic susceptibility to the endemic form of NPC
Jin-Xin Bei, Xiao-Yu Zuo, Wen-Sheng Liu, Yun-Miao Guo, Yi-Xin Zeng
Genetic and epigenetic landscape of nasopharyngeal carcinoma
Wei Dai, Hong Zheng, Arthur Kwok Leung Cheung, Maria Li Lung
MicroRNAs in nasopharyngeal carcinoma
Tara Spence, Jeff Bruce, Kenneth W. Yip, Fei-Fei Liu
Clinical utility of circulating Epstein-Barr virus DNA analysis for the management of nasopharyngeal carcinoma
Sherwood Y. H. Fung, Jacky W. K. Lam, Kwan Chee Allen Chan
Evolution of the Chinese staging system for nasopharyngeal carcinoma
Jingfeng Zong, Qingting Huang, Qiaojuan Guo, Jianji Pan
Clinical trials in nasopharyngeal carcinoma—past, present and future
Cheng Xu, Yu-Pei Chen, Jun Ma
Advances in systemic treatment for nasopharyngeal carcinoma
Wan-Ling Tan, Eng-Huat Tan, Darren Wan-Teck Lim, Quan-Sing Ng, Daniel Shao-Weng Tan, Amit Jain, Mei-Kim Ang
Immunotherapy for nasopharyngeal cancer—a review
Amit Jain, Whay Kuang Chia, Han Chong Toh
Therapeutic vaccination strategies to treat nasopharyngeal carcinoma
Graham S. Taylor, Neil M. Steven
Clinical significance of hypoxia in nasopharyngeal carcinoma with a focus on existing and novel hypoxia molecular imaging
Connie Yip, Gary J. R. Cook, Joseph Wee, Kam Weng Fong, Terence Tan, Vicky Goh
Proton therapy for nasopharyngeal carcinoma
Emma B. Holliday, Steven J. Frank
Reirradiation of locally recurrent nasopharyngeal cancer: history, advances, and promises for the future
Lin Kong, Jiade J. Lu
The International Atomic Energy Agency global initiatives on nasopharyngeal cancer treatment
Ka-On Lam, Anne W. M. Lee, Wai-Tong Ng, Kirsten I. Hopkins
Korean perspectives of nasopharynx cancer management
Yong Chan Ahn, Yeon Sil Kim

Closing Editorial

Nasopharyngeal carcinoma—some closing remarks
Joseph Tien Seng Wee, Yoke-Lim Soong, Sharon Shuxian Poh, Melvin Lee Kiang Chua


Can EGFR mutation status evolve with chemotherapy?
Eric S. Kim, David J. Stewart, Alok A. Khorana

Review Article

The spectrum of clinical trials aiming at personalizing medicine
Christophe Le Tourneau, Maud Kamal, Marie Alt, Loic Verlingue, Vincent Servois, Marie-Paule Sablin, Nicolas Servant, Xavier Paoletti
Drug designs fulfilling the requirements of clinical trials aiming at personalizing medicine
Sumithra J. Mandrekar, Daniel J. Sargent
From genomic data analysis to drug development: a new generation of trials using molecular marker assessment in breast cancer
Sophie Doisneau-Sixou, Nadia Harbeck
Melanoma adjuvant therapy
Prashanth M. Thalanayar, Sanjiv S. Agarwala, Ahmad A. Tarhini
Genotyping of cutaneous melanoma
Isabella C. Glitza, Michael A. Davies
Treatment of KIT-mutated metastatic mucosal melanoma
Kevin B. Kim, Anas Alrwas
New approaches in primary central nervous system lymphoma
Eleanor Fraser, Katherine Gruenberg, James L. Rubenstein
Molecular and clinical implementations of ovarian cancer mouse avatar models
Amira A. Zayed, Sumithra J. Mandrekar, Paul Haluska
An overview of the design and conduct of the BATTLE trials
Suyu Liu, J. Jack Lee
Designing a definitive trial for adjuvant targeted therapy in genotype defined lung cancer: the ALCHEMIST trials
Ryan S. Alden, Sumithra J. Mandrekar, Geoffrey R. Oxnard
Risk- and response-adapted strategies for the management of Hodgkin lymphoma
Marcus Remer, Peter W. M. Johnson
Prognostic scores for brain metastasis patients: use in clinical practice and trial design
Vyshak Alva Venur, Manmeet S. Ahluwalia
Strategies for preservation of memory function in patients with brain metastases
Nicholas B. Dye, Vinai Gondi, Minesh P. Mehta
Management of neoplastic meningitis
Patrick Roth, Michael Weller
Design and statistical principles of the SHIVA trial
Xavier Paoletti, Bernard Asselain, Maud Kamal, Nicolas Servant, Philippe Huppé, Ivan Bieche, Christophe Le Tourneau
Autologous tracheal replacement for cancer
Dominique Fabre, Elie Fadel, Sacha Mussot, Frederic Kolb, Nicolas Leymarie, Olaf Mercier, Thierry Le Chevalier, Philippe G. Dartevelle

Original Article

Prostate carcinoma in transgenic Lewis rats - a tumor model for evaluation of immunological treatments
Laura E. Johnson, Jordan T. Becker, Jason A. Dubovsky, Brian M. Olson, Douglas G. McNeel

Review Articles

Prevention of colorectal cancer and dietary management
Ningqi Hou, Dezheng Huo, James J. Dignam
Stage II colon cancer
David N. Church, Rachel Midgley, David J. Kerr
Mining the ACCENT database: a review and update
Lindsay A. Renfro, Qian Shi, Daniel J. Sargent
Status of hepatocellular carcinoma in South Korea
Seung Kew Yoon, Hoo Geun Chun

Statistics in Oncology Clinical Trials

Adaptive randomized phase II design for biomarker threshold selection and independent evaluation
Lindsay A. Renfro, Christina M. Coughlin, Axel M. Grothey, Daniel J. Sargent
Adaptive clinical trial designs in oncology
Yong Zang, J. Jack Lee
Statistical aspect of translational and correlative studies in clinical trials
Herbert Pang, Xiaofei Wang

Updates on Surgical Oncology

Clinical trials in lung cancer surgery and research cooperation
Wen-Zhao Zhong, Hao-Ran Zhai, Yi-Long Wu

Below are the latest Chinese Clinical Oncology articles published online ahead of print publication.


Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)
Jun Guo, Shukui Qin, Jun Liang, Tongyu Lin, Lu Si, Xiaohong Chen, Zhihong Chi, Chuanliang Cui, Nan Du, Yun Fan, Kangsheng Gu, Fang Li, Junling Li, Yongheng Li, Houjie Liang, Jiwei Liu, Man Lu, Aiping Lu, Kejun Nan, Xiaohui Niu, Hongming Pan, Guoxin Ren, Xiubao Ren, Yongqian Shu, Xin Song, Min Tao, Baocheng Wang, Wenbin Wei, Di Wu, Lingying Wu, Aiwen Wu, Xiaolin Xu, Junyi Zhang, Xiaoshi Zhang, Yiping Zhang, Huiyan Zhu, written on behalf of Chinese Society of Clinical Oncology (CSCO) Melanoma Panel

Review Article