James J. Dignam, PhD

Department of Health Studies, The University of Chicago, Chicago, Illinois, USA

James Dignam is an Associate Professor of Biostatistics in the Department of Health Studies at the University of Chicago and an Investigator in the University of Chicago Comprehensive Cancer Center. He has an extensive background in multi-center cancer clinical trial research, previously with two of the NCI Cancer Cooperative Groups, the National Surgical Adjuvant Breast and Bowel Cancer Project (NSABP) and the American College of Surgeons Oncology Group (ACoSOG), before becoming the Group Statistician for the Radiation Therapy Oncology Group (RTOG) in 2009. He has also been the principal investigator of National Institutes of Health and Susan G. Komen Breast Cancer Foundation grants in cancer research. In addition to clinical trial conduct, specific areas of research in cancer include racial/ethnic disparities in cancer prognosis and treatment response, the influence of obesity on cancer, and cancer prognosis modeling with clinical and molecular markers. Statistical research interests include clinical trial design, interim monitoring and stopping rules, and competing risks analysis. Dr. Dignam has published approximately 75 peer-reviewed articles and numerous book chapters.

Dr. Dignam also mentors graduate students in statistics and physicians in research methods, and teaches courses in introductory biostatistics, clinical trials, and survival analysis. He has also participated in numerous expert panels and review bodies with the NIH, the American Cancer Society, the American Society for Clinical Oncology, and others to address important issues in cancer research and treatment.