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Sonic hedgehog signaling pathway and gallbladder cancer: targeting with precision medicine approach

  
@article{CCO9173,
	author = {Naoko Takebe and Sherry X. Yang},
	title = {Sonic hedgehog signaling pathway and gallbladder cancer: targeting with precision medicine approach},
	journal = {Chinese Clinical Oncology},
	volume = {5},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {Gallbladder cancer is a rare disease with only about 20% of cases diagnosed in early stages. According to the American College of Surgeons/American Cancer Society National Cancer Database in the AJCC Cancer Staging Manual [2010], 5-year survival rate is only 28% for patients with stage II gallbladder cancer and single digit in stage III/IV gallbladder cancers (http://www.cancer.org/cancer/gallbladdercancer/detailedguide/gallbladder-survival-rates). It is managed by radiation therapy and chemotherapy for patients with unresectable disease in late stages and no targeted therapy are available. Thus, novel treatment approaches are needed in gallbladder cancer.},
	issn = {2304-3873},	url = {http://cco.amegroups.com/article/view/9173}
}