@article{CCO6711,
author = {Nicholas B. Dye and Vinai Gondi and Minesh P. Mehta},
title = {Strategies for preservation of memory function in patients with brain metastases},
journal = {Chinese Clinical Oncology},
volume = {4},
number = {2},
year = {2015},
keywords = {},
abstract = {Background: Cognitive decline, particularly in memory, is a side effect seen in patients with brain metastases and when severe, can have a significant impact on their quality of life. It is most often the result of multiple intersecting etiologic factors, including the use of whole brain radiation therapy, effects of which, in part, are mediated by damage within the hippocampus. A variety of clinical factors and comorbidities may impact the likelihood and severity of this cognitive decline, and affected patients should be considered for evaluation in a comprehensive neuro-rehabilitation or “brain fitness” program.
Prevention strategies of neurocognitive decline due to whole brain radiotherapy (WBRT): Avoiding WBRT is warranted for some patients with brain metastases; particularly those },
issn = {2304-3873}, url = {https://cco.amegroups.org/article/view/6711}
}