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Editorial

SETDB1 is a new promising target in HCC therapy
Carla Cicchini, Cecilia Battistelli, Marco Tripodi
Digging into lorlatinib resistance in ALK-positive lung cancer: an editorial
Francesco Facchinetti, Marcello Tiseo
Ensartinib (X-396) a novel drug for anaplastic lymphoma kinasepositive non-small cell lung cancer patients: we need smart trials to avoid wasting good bullets
Gianluca Spitaleri, Antonio Passaro, Filippo de Marinis
Does bisphosphonate treatment reduce the risk of future cancer?
Michael Pazianas, Bo Abrahamsen
Ensartinib (X-396): what does it add for patients with ALK-rearranged NSCLC
Tianhong Li, Weijie Ma, Eddie C. Tian
Who, how and what of pathology of soft tissue sarcoma
Salvatore Lorenzo Renne
Perineural invasion in oral cancer: challenges, controversies and clinical impact
Sabrina Daniela da Silva, Luiz Paulo Kowalski
Recent changes in the American Joint Commission Cancer staging of human papilloma virus related oropharyngeal cancer: validating the present and envisioning the future
Brett A. Miles
The dawn of a universal language for an emerging malignancy
Junichi Shindoh
The 8th Edition of the American Joint Committee on Cancer (AJCC8) Staging Manual: any improvement in the prognostication of oral tongue cancer?
Alhadi Almangush, Tuula Salo
Considering sarcoma staging systems and their implications to personalized care
Rick L. Haas, Michiel A. J. van de Sande
Unlocking the potential with the use of check-point inhibitor immunotherapies in metastatic prostate cancer
Swaroop Revannasiddaiah, Ishu Gupta, Santhosh Kumar Devadas
Emerging new predictive biomarkers in metastatic breast cancer: Caveolin-1 and weekly nab-paclitaxel plus gemcitabine, are we on for tomorrow?
Francesco Ricci, Christophe Le Tourneau
Occult breast cancer: the uncommon presentation of a common disease
Angela Toss, Luca Moscetti, Stefano Cascinu
Breast cancer prognostic staging and internal mammary lymph node metastases: a brief overview
Jennifer K. Plichta
Impact of hypochloremia in resected colorectal cancer patients
Mai Tsutsui, Seiichiro Yamamoto
What can National Registry data tell us about occult breast cancer?
John Benjamin Wild, Steven Thrush, Raghavan Vidya
Staging systems and nomograms in soft tissue sarcoma: outcome prediction by categorization or personalization?
William W. Tseng, Sandro Pasquali, James S. Hu, Lawrence R. Menendez, Alessandro Gronchi
A step ahead on CTHRC1, and not just reinventing the wheel!
Siddharth Turkar, Anant Ramaswamy, Vikas Ostwal

Review Article

Patient-derived xenografts: a valuable platform for clinical and preclinical research in pancreatic cancer
Yu Wang, Jiujie Cui, Liwei Wang
Targeting the tumor microenvironment for pancreatic ductal adenocarcinoma therapy
Yi-Fan Zhang, Shu-Heng Jiang, Li-Peng Hu, Pei-Qi Huang, Xu Wang, Jun Li, Xue-Li Zhang, Hui-Zhen Nie, Zhi-Gang Zhang