Article Abstract

Chimeric antigen receptor (CAR) T and other T cell strategies for pancreas adenocarcinoma

Authors: Anna M. Varghese

Abstract

Abstract: Treatments in metastatic pancreas cancer remain based in cytotoxic chemotherapy, and novel treatment strategies are needed. Building on the emerging role of T cell therapy in hematologic malignancies and our understanding of the underlying biology of pancreas cancer, research is growing in the role of T cell therapy for patients with solid tumors in general and more specifically patients with pancreas cancer. This review will focus on describing the biology of T cell therapy and its current applications in pancreas cancer.

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